Nutrition Metabolic Laboratory

The Metabolic Laboratory includes a metabolic kitchen, dining area for subjects, computer facilities, a state of the art software, Nutrition Data System for Research, to analyze nutrient intake, ProNutra software to design metabolic diets of specific nutrient composition, food models, and equipment for anthropometric and blood pressure measurement.

Dr. Shah has conducted a number of research studies including: comparison of 24 hour energy expenditure in formerly obese and naturally lean women at different levels of physical activity; effect of a low-fat ad-libitum diet compared with a calorie controlled diet on long-term weight loss maintenance in moderately obese women; and effect of culturally specific cholesterol-lowering diets on serum cholesterol in African-American and Hispanic patients with systemic lupus erythematosus. She is currently involved in several research projects with colleagues at UT Southwestern Medical Center at Dallas and some of the studies, funded by a large NIH grant, include treatment of hyperlipidemia in HIV positive patients by fish oil therapy, aerobic exercise, and leptin therapy.

The research goals of this laboratory include evaluating the impact of diets of varying macronutrient composition in combination with exercise on cardiovascular risk factors; designing and evaluating interventions that lead to improved long-term adherence to diet and exercise recommendations; and analyzing the impact of altering the energy density and appearance of a meal on energy intake. The laboratory is also used for conducting class laboratory exercises at both the undergraduate and graduate levels, and senior research projects by undergraduate Movement Science students.

Peer Reviewed Publications

• Shah M, Adams-Huet B, Bantle JP, Henry RR, Griver KA, Raatz SK, Brinkley L, Reaven GM, Garg A. Effect of a high-carbohydrate versus a high-cis-monounsaturated fat diet on blood pressure in patients with type 2 diabetes. Diabetes Care 2005;28(11):2607-12.
• Shah M, Tierney K, Adams-Huet B, Boonyavarakul A, Jacob K, Quittner C, Dinges WL, Peterson D, Garg A. The role of diet, exercise, and smoking in dyslipidaemia in HIV-infected patients with lipodystrophy. HIV Medicine 2005;6:291-8.
• Shah M, Adams-Huet B, Grundy SM, Garg A. Effect of a high-carbohydrate diet versus a high-cis-monounsaturated fat diet on lipid and lipoproteins in individuals with and without type 2 diabetes mellitus. Nutrition Research 2004;24:969-79.
• Shah M, Adams-Huet B, Kavanaugh A, Coyle Y, Lipsky P. Nutrient intake and diet quality in patients with systemic lupus erythematosus on a culturally sensitive cholesterol-lowering dietary program. J of Rheumatology 2004;31(1):71-75.
• Shah M, Coyle Y, Kavanaugh A, Adams-Huet B, Lipsky P. Focus group assessment of culturally specific cholesterol-lowering menus prepared for Mexican-American patients with systemic lupus erythematosus. Inter Elect J Hlth Educ 2004;1:9-19.
• Shah M, Kavanaugh, Coyle Y, Adams-Huet B, Lipsky P. Effect of a culturally sensitive cholesterol-lowering diet program on lipid and lipoproteins, body weight, nutrient intakes, and quality of life in patients with systemic lupus erythematosus. J of Rheumatology 2002;29:2122-8.
• Shah M, Coyle Y, Kavanaugh A, Adams-Huet B, Lipsky P. Development and initial evaluation of a culturally sensitive cholesterol lowering diet program for Mexican and African American patients with systemic lupus erythematosus. Arthritis Care and Research 2000;13(4):205-212.
• Shah M, McGovern M, Baxter J, Garg A: Nutrient and food intake in obese women on a low-fat or low-calorie diet. Am J Health Prom 1996;10(3):179-182.
• Shah M, Garg A: High fat- and high-carbohydrate diets and energy balance. Diab Care 1996;19(10):1142-1152.
• Shah M, McGovern P, French S, Baxter J: Comparison of a low fat ad-libitum complex carbohydrate and a low energy diet in moderately obese women. Am J Clin Nutr 1994; 59:980-984.
• Lehmann MH, Thomas A, Nabih M, Stainman RT, Fromm BS, Shah M, Norsted SW:  Sudden death in recipients of first generation implantable cardioverter defibrillator: Analysis of terminal events. J Intervent Cardiol 1994; 7:487-503.
• Shah M, French S., Jeffery RW, McGovern P, Forster JL, Lando HA: Correlates of high calorie/fat foods in a worksite population: The Healthy Worker Project. Addictive Behaviors 1993;18:583-594.
• Shah M, Hannan PJ, Jeffery RW: Secular trends in body mass index in the adult population of three communities from the upper mid-western part of the USA: The Minnesota Heart Health Program.  Int J Obes 1991;15:499-503.
• Shah M, Jeffery RW: Is obesity due to overeating and inactivity, or to a defective metabolic rate? A review. Annals Behavioral Med 1991;13:73-81.
• Shah M, Jeffery RW, Laing B, Savre SG, VanNatta M, Strickland D: Hypertension Prevention Trial (HPT): Food pattern changes resulting from intervention on sodium, potassium, and energy intake. J Am Diet Assoc 1990;90:69-76.
• Shah M, Jeffery RW, Hannan PJ, Onstad L. Relationship between socio-demographic and behavior factors, and body mass index in a population with high-normal blood pressure: Hypertension Prevention Trial. Europ J Clin Nutr 1989;43:583-596.
• Shah M, Miller DS, Geissler CA. Lower metabolic rates of post-obese versus lean women: thermogenesis, basal metabolic rate and genetics. Europ J Clin Nutr 1988;42:741-752.
• Shah M, Geissler CA, Miller DS. Metabolic rate during and after aerobic exercise in post-obese and lean women. Europ J Clin Nutr 1988;42:455-464.
• Geissler CA, Miller DS, Shah M. The daily energy expenditure of the post obese and the lean. Am J Clin Nutr 1987;45:914-920.